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Donald F Brophy Selected Research

Traumatic Shock

1/2018Interventional vitamin C: A strategy for attenuation of coagulopathy and inflammation in a swine multiple injuries model.
7/2011Examining platelet-fibrin interactions during traumatic shock in a swine model using platelet contractile force and clot elastic modulus.
12/2010Systemic central venous oxygen saturation is associated with clot strength during traumatic hemorrhagic shock: A preclinical observational model.
1/2010Coagulopathy and traumatic shock: characterizing hemostatic function during the critical period prior to fluid resuscitation.

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Donald F Brophy Research Topics

Disease

14Hemorrhage
11/2021 - 08/2004
8Hemophilia A (Haemophilia)
01/2022 - 09/2010
7Wounds and Injuries (Trauma)
11/2021 - 01/2010
7Sepsis (Septicemia)
10/2019 - 09/2007
7Chronic Renal Insufficiency
01/2017 - 08/2004
5Inflammation (Inflammations)
12/2019 - 01/2014
5Chronic Kidney Failure (Chronic Renal Failure)
01/2017 - 08/2004
5Anemia
01/2012 - 11/2005
4Traumatic Shock
01/2018 - 01/2010
4Shock
01/2018 - 01/2010
3Thrombosis (Thrombus)
11/2021 - 01/2009
3Hemorrhagic Shock
11/2019 - 12/2010
3Critical Illness (Critically Ill)
04/2013 - 10/2010
2Thrombocytopenia (Thrombopenia)
11/2021 - 10/2010
2Fibrosis (Cirrhosis)
01/2020 - 04/2013
2Tics (Tic)
11/2019 - 01/2019
2Multiple Trauma (Multiple Injuries)
11/2019 - 01/2018
2Hypothermia
11/2019 - 01/2018
2Infections
09/2014 - 09/2007
2Multiple Organ Failure (MODS)
09/2014 - 01/2014
2Acute Kidney Injury (Acute Renal Failure)
04/2013 - 09/2002
1Porcine Reproductive and Respiratory Syndrome (PRRS)
12/2019
1Venous Thrombosis (Deep-Vein Thrombosis)
12/2019
1Acidosis
11/2019
1Bone Fractures (Bone Fracture)
11/2019
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
10/2019
1Respiratory Insufficiency (Respiratory Failure)
10/2019
1Vascular System Injuries
10/2019
1Colonic Neoplasms (Colon Cancer)
01/2019
1Thrombasthenia (Glanzmann Thrombasthenia)
01/2019
1Heart Failure
11/2018
1Ischemia
01/2018
1Hypotension (Low Blood Pressure)
01/2018
1Acute Lung Injury
01/2018
1Angiodysplasia
11/2017
1Liver Neoplasms (Liver Cancer)
09/2015

Drug/Important Bio-Agent (IBA)

7Ascorbic Acid (Vitamin C)FDA LinkGeneric
11/2019 - 08/2013
5Enoxaparin (Lovenox)FDA LinkGeneric
12/2019 - 08/2004
5Fibrinogen (Factor I)FDA Link
01/2016 - 01/2010
4Hemostatics (Antihemorrhagics)IBA
01/2022 - 01/2010
4recombinant FVIIa (rFVIIa)FDA Link
01/2020 - 09/2010
3Factor VIIa (Activated Factor VII)IBA
01/2022 - 09/2010
3ThrombinFDA Link
07/2021 - 08/2004
3Thromboplastin (Tissue Factor)IBA
12/2019 - 01/2018
3Proteins (Proteins, Gene)FDA Link
11/2019 - 11/2005
3Oxygen (Dioxygen)IBA
11/2019 - 12/2010
3Biomarkers (Surrogate Marker)IBA
10/2019 - 12/2010
2LipidsIBA
11/2021 - 12/2019
2Pharmaceutical PreparationsIBA
07/2021 - 12/2006
2Heparin (Liquaemin)FDA LinkGeneric
12/2019 - 01/2019
2Starch (Cornstarch)IBA
11/2019 - 01/2018
2Blood Proteins (Serum Proteins)IBA
11/2019 - 09/2015
2Blood Coagulation Factors (Coagulation Factor)IBA
09/2019 - 09/2015
2FibrinIBA
08/2015 - 07/2011
2SolutionsIBA
09/2014 - 08/2013
2HematinicsIBA
01/2012 - 01/2010
2ErythropoietinFDA Link
01/2012 - 11/2005
2IronIBA
01/2012 - 09/2007
1EmulsionsIBA
11/2021
1MicellesIBA
11/2021
1lipoprotein-associated coagulation inhibitor (TFPI)IBA
07/2021
1Clopidogrel (Plavix)FDA Link
01/2020
1Docosahexaenoic AcidsIBA
12/2019
1Eicosapentaenoic AcidIBA
12/2019
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
12/2019
1Pattern Recognition ReceptorsIBA
12/2019
1EnzymesIBA
12/2019
1Colloids (Colloid)IBA
11/2019
1ProteomeIBA
11/2019
1Complement System Proteins (Complement)IBA
11/2019
1C-Reactive ProteinIBA
10/2019
1ThrombomodulinIBA
10/2019
1marstacimabIBA
09/2019
1Factor IX (Coagulation Factor IX)FDA LinkGeneric
09/2019
1emicizumabIBA
01/2019
1Adenosine Diphosphate (ADP)IBA
01/2019
1PolymersIBA
01/2019
1IntegrinsIBA
01/2019
1P-SelectinIBA
01/2019
1p38 Mitogen-Activated Protein KinasesIBA
01/2019
1Saline SolutionIBA
01/2018
1Crystalloid SolutionsIBA
01/2018
1Messenger RNA (mRNA)IBA
01/2018
1PlasminogenIBA
01/2018
1Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
01/2018
1Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
11/2017
1Octreotide (Sandostatin)FDA LinkGeneric
11/2017
1SphingolipidsIBA
01/2017
1apixabanIBA
01/2017
1methionine sulfoxideIBA
01/2016
1Protease Inhibitors (Protease Inhibitor)IBA
09/2015
1ApolipoproteinsIBA
09/2015

Therapy/Procedure

8Therapeutics
01/2019 - 11/2005
5Resuscitation
11/2019 - 01/2010
5Renal Dialysis (Hemodialysis)
01/2017 - 01/2007
3Heart-Assist Devices
11/2018 - 05/2017
2Intravenous Infusions
11/2021 - 01/2014
2Peritoneal Dialysis
01/2017 - 01/2014
2Parenteral Infusions
09/2014 - 08/2013
1Precision Medicine
01/2018